| 释义 |
Sézary, n. Path.
(ˈsɛzərɪ, ‖ sezari)
[The name of Albert Sézary (1880–1956), French dermatologist, who described the condition in 1938 (Bull. Soc. Fr. Derm. Syph. XLV. 254).]
Used attrib. or in the possessive, esp. as Sézary('s) syndrome, to designate a type of cutaneous lymphoma with symptoms including exfoliative dermatitis, intense pruritus, and the presence in the blood of atypical T lymphocytes with convoluted nuclei (sometimes called Sézary cells). (The syndrome is thought to be caused by human T cell leukaemia virus type 1, HTLV-1.)
1953Brit. Med. Jrnl. 16 May 1087/1 (heading) Sézary's reticulosis with exfoliative dermatitis. 1955Ibid. 29 Jan. 258/1 Sézary cells in air-dried Romanovski films..are approximately twice the size of normal polymorphs. Ibid. 258/2 The features of Sézary's syndrome are intense pruritus, generalized erythrodermia, pigmentation, and superficial lymphadenopathy, associated with the presence of unusual monocytoid cells in the blood. 1961Jrnl. Amer. Med. Assoc. 19 Aug. 471/1 In our experience, erythrodermic mycosis fungoides is the condition most frequently confused with the Sézary syndrome. 1968Blood XXXI. 722 The nucleus of the lymphocyte has a round contour or a single deep notch and can be easily distinguished from the Sézary cell. 1978M. Burnet Endurance of Life x. 145 A type of lymphocytic leukaemia, spoken of as Sezary's disease. |