busulfan
/bjuːˈsʌlfan/(also busulphan) Pharmacology
noun
A drug which is an alkylating agent with a destructive effect on bone marrow, used especially in the treatment of chronic myeloid leukaemia and in the preparation of patients for bone marrow transplantation.
- Chemical name: 1,4-di(methanesulphonyloxy)butane; C6H14O6S2. Busulfan is the International Nonproprietary Name (1996). Busulphan is the British Approved Name (1997). A trademark for this drug is Myleran..
Origin
1950s; earliest use found in The British Medical Journal. From bu- + sulf-, elements of the chemical name + -an.
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