单词	homozygote
释义	homozygote /ˌhɒmə(ʊ)ˈzʌɪɡəʊt / /ˌhəʊmə(ʊ)ˈzʌɪɡəʊt/ noun Genetics An individual having two identical alleles of a particular gene or genes and so breeding true for the corresponding characteristic. Compare with heterozygote.This is because inbred individuals are more likely to express deleterious alleles as homozygotes than are outbreds.... Similarly, inbreeding decreases the effective size of selection but unmasks deleterious alleles in homozygotes. Expression in heterozygotes and homozygotes is apparently identical. Derivatives homozygosity noun ... This was considered an appropriate technique since there was a high incidence of homozygosity and single-site heterozygosity. Increased individual homozygosity and decreased population-wide genetic diversity should be disadvantageous. For partially recessive mutations, high levels of homozygosity in inbred populations may partially oppose these effects. homozygous /ˌhɒmə(ʊ)ˈzʌɪɡəs / /ˌhəʊmə(ʊ)ˈzʌɪɡəs / adjective ... In human patients, homozygous as well as heterozygous mutations are associated with disease. Thirteen animals were heterozygous while one was homozygous for this amino acid substitution. Because of perpetual inbreeding, each of the strains has an essentially homozygous genome.
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