| Acronym | Definition |
|---|
| HPEP➣HTTP (Hypertext Transfer Protocol) Performance Enhancement Proxy |
| HPEP➣Humboldt Park Empowerment Partnership |
| HPEP➣Heavy Power Equipment Plant (India) |
| HPEP➣Health Professionals Education Project (various locations) |
| HPEP➣High Performance Engineering Polymer (composition) |
| HPEP➣Haemophilia Programme Enhancement Project (est. 1991; British Columbia, Canada) |