glycine cleavage complex


gly·cine cleav·age com·plex

a complex of several proteins that catalyze the reversible reaction of glycine with tetrahydrofolate to produce CO2, NH3, and N5,N10-methylenetetrahydrofolate; a deficiency of this enzyme (or one of its subunits) will result in nonketotic hyperglycinemia. Synonym(s): glycine synthase