Bruton's disease


Bruton's disease

[′brüt·ənz di‚zēz] (immunology) A hereditary type of agammaglobulinemia that is a sex-linked recessive disorder characterized by a deficiency of all types of immunoglobulins, reflecting a failure of the entire humoral antibody marrow system; the thymus may be normal, but the lymph nodes and spleen lack lymph cell follicles.