释义 |
CCL23
CCL23 A gene on chromosome 17q12 that encodes a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. CCL23 binds CCR1; it is chemotactic for resting T lymphocytes and monocytes, has some effect on neutrophils and no effect on activated T lymphocytes. CCL23 is a strong suppressor of colony formation by multipotential haematopoietic stem cells. |