dextran

dex·tran

D0187200 (dĕk′străn′, -strən)n. Any of a group of branched polysaccharides with various molecular weights that are used to prevent thrombosis, as plasma volume expanders, and as food additives.

[dextr(ose) + -an.]

dextran

(ˈdɛkstrən) n (Biochemistry) biochem a polysaccharide produced by the action of bacteria on sucrose: used as a substitute for plasma in blood transfusions[C19: from dextro- + -an]

dex•tran

(ˈdɛk strən)

n. a viscous polysaccharide produced by bacterial action on sucrose: used in confections and lacquers and as a blood-plasma extender. [1875–80; dextr (ose) + -an²]

Dextran

dextran

[′dek ‚stran] (biochemistry) Any of the several polysaccharides, (C₅H₁₀O₅)_n, that yield glucose units on hydrolysis.

Dextran

(C₆H₁₀O₅)_n, a polysaccharide of bacterial origin, a polymer of glucose. The molecular weight can be as high as 10,000,000. In the linear part of the dextran molecule the glucose residues are joined by bonds between the first and sixth carbon atoms; branching is due to bonds between the first and fourth, first and third, and first and second atoms. Dextran is obtained by growing microorganisms of the genus Leuconostoc in an artificial culture medium. Dextran, in the form of a partially hydrolyzed solution with not less than 90 percent 1.6 linkages and a molecular weight of about 60,000 is used clinically as a blood plasma substitute. The preparation provides for a normal osmotic pressure corresponding to that of blood. Modified dextran, so-called Sephadex, is used in chromatography.

dextran

[dek´stran] a water-soluble polysaccharide of glucose produced by the action of Leuconostoc mesenteroides on sucrose; used as an extender" >artificial plasma extender.

dex·tran

(deks'tran), 1. Any of several water-soluble high molecular weight glucose polymers (ranging between MW 1,000 and 40,000,000); produced by the action of members of the family Lactobacillaceae and certain other microorganisms on sucrose; used in isotonic sodium chloride solution for the treatment of shock, and in distilled water for the relief of the edema of nephrosis; lower molecular weight dextran (for example, MW 40,000 designated as dextran 40) improves blood flow in areas of stasis by reducing cellular aggregation.
See also: dextransucrase. 2. α-1,6-glucan with branch points (1,2; 1,3; 1,4) that are spaced in a manner characteristic of the individual species; used as plasma substitutes or expanders.
See also: dextransucrase.

dextran

(dĕk′străn′, -strən)n. Any of a group of branched polysaccharides with various molecular weights that are used to prevent thrombosis, as plasma volume expanders, and as food additives.

dextran

Transfusion medicine Dextran-40, dextran-70, dextran-1 A colloid-type volume expander consisting of a large glycogen-like molecules which may occasionally be used in surgical blood management by hemodilution; these substances have the desired properties of being viscid, and gelatinous, resulting in oncotic pressure to retain fluids in vessels; they are widely used as replacement fluids and volume expanders Pros ↓ Allogeneic transfusions, ↓ postoperative bleeding, ↓ blood viscosity Cons Interferes with platelet and RBC function, crossmatching; may cause anaphylaxis and peripheral edema. See Colloid solutions, Crystalloids, Hemodilution, Surgical blood management.

dex·tran

(deks'tran) Any of several water-soluble high molecular weight glucose polymers; used in isotonic sodium chloride solution for the treatment of shock, and in distilled water for the relief of the edema of nephrosis; lower molecular weight dextran.
See also: dextransucrase

dex·tran

(deks'tran) Any of several water-soluble high molecular weight glucose polymers; used in isotonic sodium chloride solution to treat shock and to relieve edema of nephrosis.

单词	dextran
释义	dextran dex·tran D0187200 (dĕk′străn′, -strən)n. Any of a group of branched polysaccharides with various molecular weights that are used to prevent thrombosis, as plasma volume expanders, and as food additives. [dextr(ose) + -an.] dextran (ˈdɛkstrən) n (Biochemistry) biochem a polysaccharide produced by the action of bacteria on sucrose: used as a substitute for plasma in blood transfusions[C19: from dextro- + -an] dex•tran (ˈdɛk strən) n. a viscous polysaccharide produced by bacterial action on sucrose: used in confections and lacquers and as a blood-plasma extender. [1875–80; dextr (ose) + -an²] Dextran dextran [′dek ‚stran] (biochemistry) Any of the several polysaccharides, (C₅H₁₀O₅)_n, that yield glucose units on hydrolysis. Dextran (C₆H₁₀O₅)_n, a polysaccharide of bacterial origin, a polymer of glucose. The molecular weight can be as high as 10,000,000. In the linear part of the dextran molecule the glucose residues are joined by bonds between the first and sixth carbon atoms; branching is due to bonds between the first and fourth, first and third, and first and second atoms. Dextran is obtained by growing microorganisms of the genus Leuconostoc in an artificial culture medium. Dextran, in the form of a partially hydrolyzed solution with not less than 90 percent 1.6 linkages and a molecular weight of about 60,000 is used clinically as a blood plasma substitute. The preparation provides for a normal osmotic pressure corresponding to that of blood. Modified dextran, so-called Sephadex, is used in chromatography. dextran dextran [dek´stran] a water-soluble polysaccharide of glucose produced by the action of Leuconostoc mesenteroides on sucrose; used as an extender" >artificial plasma extender. dex·tran (deks'tran), 1. Any of several water-soluble high molecular weight glucose polymers (ranging between MW 1,000 and 40,000,000); produced by the action of members of the family Lactobacillaceae and certain other microorganisms on sucrose; used in isotonic sodium chloride solution for the treatment of shock, and in distilled water for the relief of the edema of nephrosis; lower molecular weight dextran (for example, MW 40,000 designated as dextran 40) improves blood flow in areas of stasis by reducing cellular aggregation. See also: dextransucrase. 2. α-1,6-glucan with branch points (1,2; 1,3; 1,4) that are spaced in a manner characteristic of the individual species; used as plasma substitutes or expanders. See also: dextransucrase. dextran (dĕk′străn′, -strən)n. Any of a group of branched polysaccharides with various molecular weights that are used to prevent thrombosis, as plasma volume expanders, and as food additives. dextran Transfusion medicine Dextran-40, dextran-70, dextran-1 A colloid-type volume expander consisting of a large glycogen-like molecules which may occasionally be used in surgical blood management by hemodilution; these substances have the desired properties of being viscid, and gelatinous, resulting in oncotic pressure to retain fluids in vessels; they are widely used as replacement fluids and volume expanders Pros ↓ Allogeneic transfusions, ↓ postoperative bleeding, ↓ blood viscosity Cons Interferes with platelet and RBC function, crossmatching; may cause anaphylaxis and peripheral edema. See Colloid solutions, Crystalloids, Hemodilution, Surgical blood management. dex·tran (deks'tran) Any of several water-soluble high molecular weight glucose polymers; used in isotonic sodium chloride solution for the treatment of shock, and in distilled water for the relief of the edema of nephrosis; lower molecular weight dextran. See also: dextransucrase dex·tran (deks'tran) Any of several water-soluble high molecular weight glucose polymers; used in isotonic sodium chloride solution to treat shock and to relieve edema of nephrosis.
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