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DictionarySeehistoplasmosisDarling disease
his·to·plas·mo·sis (his'tō-plaz-mō'sis), A widely distributed infectious disease caused by Histoplasma capsulatum; occurs occasionally in outbreaks; usually acquired by inhalation of spores of the fungus in soil dust and manifested by a self-limited pneumonia. In patients with emphysema, infection may be chronic and cause pulmonary fibrocavitary disease resembling tuberculosis; in immunosuppressed patients, and rarely, in otherwise healthy persons, histoplasmosis may cause disseminated disease of the reticuloendothelial system, which is manifested by fever, emaciation, splenomegaly, and leukopenia. Synonym(s): Darling diseaseDarling disease (dar'ling) [Samuel Taylor Darling, U.S. pathologist, 1872–1925] Histoplasmosis.Darling, Samuel Taylor, U.S. physician in Panama, 1872-1925. Darling disease - a widely distributed infectious disease caused by Histoplasma capsulatum and manifested by a primary benign pneumonitis. Synonym(s): histoplasmosis |