desquamative interstitial pneumonia

des·qua·ma·tive in·ter·sti·tial pneu·mo·ni·a (DIP),

diffuse proliferation of alveolar epithelial cells, which desquamate into the air sacs and become filled with macrophages, accompanied by interstitial cellular infiltration and fibrosis; gradual onset of dyspnea and nonproductive cough occurs.

desquamative interstitial pneumonia

A generally mild, nonspecific interstitial pulmonary reaction that is a double misnomer—as it is neither desquamative nor interstitial—which is characterised by diffuse deposition of haemosiderotic macrophages. DIP is often idiopathic but may be associated with inhalation of inorganic dusts.
Demographics
Most patients are smokers and adults; DIP rarely occurs in children, in whom it has a worse prognosis.
Prognosis
Better prognosis and response to steroids than UIP (in adults).
Imaging
Bilateral ground-glass opacification.

DiffDx
Smoking (RBILD), amiodarone therapy, eosinophilic pneumonia, pulmonary alveolar proteinosis.
Management
Corticosteroids.

单词	desquamative interstitial pneumonia
释义	DictionarySeedip desquamative interstitial pneumonia des·qua·ma·tive in·ter·sti·tial pneu·mo·ni·a (DIP), diffuse proliferation of alveolar epithelial cells, which desquamate into the air sacs and become filled with macrophages, accompanied by interstitial cellular infiltration and fibrosis; gradual onset of dyspnea and nonproductive cough occurs. desquamative interstitial pneumonia A generally mild, nonspecific interstitial pulmonary reaction that is a double misnomer—as it is neither desquamative nor interstitial—which is characterised by diffuse deposition of haemosiderotic macrophages. DIP is often idiopathic but may be associated with inhalation of inorganic dusts. Demographics Most patients are smokers and adults; DIP rarely occurs in children, in whom it has a worse prognosis. Prognosis Better prognosis and response to steroids than UIP (in adults). Imaging Bilateral ground-glass opacification. DiffDx Smoking (RBILD), amiodarone therapy, eosinophilic pneumonia, pulmonary alveolar proteinosis. Management Corticosteroids. FinancialSeeDipAcronymsSeediploma
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