单词 | capacitation |
释义 | capacitationcapacitation[kə‚pas·ə′tā·shən]capacitationcapacitation[kah-pas″ĭta´shun]ca·pac·i·ta·tion(kă-pas'i-tā'shŭn),capacitationA biochemical event in mammals that consists of the post-ejaculation maturation of sperm, which are capable of penetrating the zona pellucida and fertilising an oocyte. Capacitation is due to exposure to secretions—sterol binding albumin, lipoproteins, proteases and glycosidases—in the uterus, and requires the correct concentration of the tripeptide fertilisation promoting peptide, which is present in seminal fluid. Capacitation destabilises the acrosomal sperm-head membrane, facilitating binding of a sperm to the oocyte by removing steroids (e.g., cholesterol) and non-covalently bound seminal glycoprotein; the process is reversible and includes all of the events up to the acrosome reaction, which is irreversible.capacitationReproductive medicine The postrelease maturation in sperm, which are capable of penetrating the zona pellucida and fertilizing an oocyte after exposure to secretions in the ♀ genital tract. Cf Acrosome reaction.ca·pac·i·ta·tion(kă-pas'i-tā'shŭn)capacitationchanges occurring in SPERM while inside the female reproductive tract, where the acidic environment causes alterations to the cell membrane of the sperm that make possible its adhesion to the secondary OOCYTE. |
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