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B lymphocyte
B lymphocyte also B-lym·pho·cyte B0352600 (bē′lĭm′fə-sīt′)n. See B cell.B cell
n. 1. Also called B lymphocyte. a type of white blood cell that circulates in the blood and lymph and produces antibody upon encountering any antigen that has a molecular arrangement complementary to the antibody. 2. beta cell. [1970–75] Thesaurus| Noun | 1. |  B lymphocyte - a lymphocyte derived from bone marrow that provides humoral immunity; it recognizes free antigen molecules in solution and matures into plasma cells that secrete immunoglobulin (antibodies) that inactivate the antigensB celllymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection |
B lymphocyte
B lymphocyte[¦bē ′lim·fə‚sīt] (immunology) B cell B lymphocyte
B lym·pho·cytean immunologically important lymphocyte that is not thymus dependent, is short-lived, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins; that is, it is the precursor of the plasma cell and expresses surface immunoglobulins (SIGS) but does not release them. It does not play a direct role in cell-mediated immunity. B lymphocyte can be characterized immunophenotypically by CD19 surface markers.
See also: T lymphocyte. Synonym(s): B cell (2) B lymphocyte also B-lymphocyte (bē′lĭm′fə-sīt′)n. See B cell.B cell One of the two major classes of lymphocytes, which comprises 30% of circulating lymphocytes and is concentrated in the follicular zones of lymphoid tissue (in contrast T cells, which are located in the deep cortex). B cells are responsible for antibody production, a transformation evoked by interaction with the appropriate CD4 T-helper cells. Igs are responsible for specific defence against viruses and bacteria, immune surveillance (cytolysis of potentially malignant “self” cells, mediation of antibody-dependent cell cytotoxicity), allergic reactions, formation of antigen-antibody complexes and production of cytokines; surface and cytoplasmic antigens indicate the degree of B-cell maturation and function. Cytoplasmic IgM is present in pre-B cells and surface Ig in mature B lymphoctytes and plasma cells; complement receptors are seen in mature cells. B cell markers include CD9, CD10, CD19, CD20, CD24, Fc receptor, B1, BA-1 and B4 Ia.B lym·pho·cyte (lim'fŏ-sīt) A lymphocyte that resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins, i.e., it is the precursor of the plasma cell and expresses immunoglobulins on its surface but does not release them. It does not play a direct role in cell-mediated immunity.
See also: T lymphocyteB lymphocyteA type of lymphocyte that circulates in the blood and lymph and produces antibodies when it encounters specific antigens. B lymphocytes are also called B cells.Mentioned in: LymphocytopeniaB lym·pho·cyte (lim'fŏ-sīt) Immunologically important lymphocyte that is not thymus dependent, is short lived, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins. B lymphocyte
Synonyms for B lymphocytenoun a lymphocyte derived from bone marrow that provides humoral immunitySynonymsRelated Words |