thiamine pyrophosphate

thiamine pyrophosphate:

see coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
..... Click the link for more information. ; vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
..... Click the link for more information. .

Thiamine Pyrophosphate

(also cocarboxylase), a coenzyme that participates in the enzymic transformations of α-keto acids and keto sugars; it is present in all animal and plant tissues, as well as in microorganisms.

The catalytic activity of thiamine pyrophosphate is associated with ionization of the carbon atom in the second position of the thiazole ring, to which a molecule of a substrate attaches itself. In industry, thiamine pyrophosphate is obtained from thiamine and pyrophosphoric acid. (For the medical use of thiamine pyrophosphate, SeeCOCARBOXYLASE.)

REFERENCE

Kokarboksilaza i drugie tiaminfosfaty. Minsk, 1974.

thiamine pyrophosphate

[′thī·ə·mən ¦pī·rō′fä‚sfāt] (biochemistry) The coenzyme or prosthetic component of carboxylase; catalyzes decarboxylation of various α-keto acids. Also known as cocarboxylase.

thiamine pyrophosphate

(thi'a-min, -men? pi?ro-fos'fat?) An enzyme important in carbohydrate metabolism. It is the active form of thiamine. In people suspected of malnutrition, administering thiamine before the infusion of glucose-containing solutions prevents brain damage (Wernicke-Korsakoff's encephalopathy). Synonym: cocarboxylase

Thiamine pyrophosphate (TPP)

The coenzyme containing thiamine that is essential in converting glucose to energy.Mentioned in: Beriberi

thiamine pyrophosphate

thiamine pyrophosphate

thiamine pyrophosphate:

Thiamine Pyrophosphate

REFERENCE

thiamine pyrophosphate

thiamine pyrophosphate

thiamine pyrophosphate

Thiamine pyrophosphate (TPP)

thiamine pyrophosphate

Synonyms for thiamine pyrophosphate

noun a coenzyme important in respiration in the Krebs cycle

Synonyms

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