TMPRSS6

A gene on chromosome 22q12.3 that encodes a liver-specific serine protease which hydrolyses various proteins, including type-I collagen, fibronectin, fibrinogen and, with lesser efficiency, urokinase-type plasminogen. It may play a role in matrix remodelling in the liver and is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses HAMP promoter activation. TMPRSS6 is also the former name for what is now designated TMPRSS13.
Molecular pathology
Defects in TMPRSS6 cause iron-refractory iron deficiency anaemia (IRIDA).

单词	tmprss6
释义	TMPRSS6 TMPRSS6 A gene on chromosome 22q12.3 that encodes a liver-specific serine protease which hydrolyses various proteins, including type-I collagen, fibronectin, fibrinogen and, with lesser efficiency, urokinase-type plasminogen. It may play a role in matrix remodelling in the liver and is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses HAMP promoter activation. TMPRSS6 is also the former name for what is now designated TMPRSS13. Molecular pathology Defects in TMPRSS6 cause iron-refractory iron deficiency anaemia (IRIDA).
随便看	cleavage l's cleavage nucleus cleavage of lateral epitaxial films for transfer cleavage of minerals cleavage plane cleavage/polyadenylation factor i cleavage polyadenylation specificity factor cleavage product cleavages cleavage signal-1 protein cleavage site cleavage spindle cleavage stimulation factor cleavase fragment length polymorphism cleave cleave board cleaved cleaved amplified polymorphic sequence cleaved cell cleaved edge overgrowth cleaved surface cleavelandite cleaveland, moses cleaver cleaver-brooks representatives association