| 单词 | pten-hamartoma-tumour syndromes |
| 释义 | PTEN-hamartoma-tumour syndromesPTEN-hamartoma-tumour syndromesA group of four syndromes—Bannayan-Riley-Ruvalcaba syndrome, Cowden syndrome, Proteus syndrome and Proteus-like syndrome—all of which are caused by a mutation in PTEN, a gene located on chromosome 10q23.3, which encodes PTEN, a tumour suppressor gene that down-regulates the AKT/PKB-signalling pathway. |
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