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单词 artificial chromosome
释义

artificial chromosome


artificial chromosome

n. A large sequence of DNA, such as a human artificial chromosome or a bacterial artificial chromosome, that is constructed in a laboratory to function like a chromosome or inserted into a cell to be replicated and expressed. Artificial chromosomes have been used in gene mapping and in modeling genetic diseases.

artificial chromosome


artificial chromosome

[‚ärd·ə¦fish·əl ′krō·mə‚sōm] (genetics) A functional chromosome constructed by genetic engineering, having a centromere (and a telomere at each end, if linear rather than circular) and thus transmissable in cell division after introduction into a cell.

artificial chromosome


artificial chromosome

n. A large sequence of DNA, such as a human artificial chromosome or a bacterial artificial chromosome, that is constructed in a laboratory to function like a chromosome or inserted into a cell to be replicated and expressed. Artificial chromosomes have been used in gene mapping and in modeling genetic diseases.

artificial chromosome

The result of a biotechnology still at an experimental stage. Human chromosomes, consisting of a centromere of highly repetitive DNA sequences, telomeric DNA, a marker gene and some random sequences of genomic DNA, have been successfully prepared. When these ingredients were introduced into a human cell line they became coated with histone proteins and formed highly coiled structures. They also replicated and passed on copies to daughter cells through more than 200 cell divisions.
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更新时间:2024/12/23 10:33:07