tissue factor pathway inhibitor


tissue factor pathway inhibitor

(extrinsic factor) lipoprotein-associated coagulation inhibitor Hematology A coagulation factor X-dependent inhibitor of the factor VIIa/tissue factor complex; it is a plasma lipoprotein that regulates procoagulant effects of tissue factor; with Ca2+ and phospholipid, TFPI binds to and inhibits either free factor Xa or factors Xa and VIIa when associated with tissue factor-factor VIIa-Xa complex