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RALES Cardiology A series of trials–Randomized Aldactone Evaluation Study that demonstrated that the addition of Aldactone®–spironolactone to standard therapies–eg, ACE inhibitors, resulted in a 27% ↓ in total mortality in severe CHF Pts with systolic left ventricular dysfunction. See Spironolactone. rales Abnormal rattling sounds accompanying the breath sounds and heard through a STETHOSCOPE during examination of the chest. They are caused by air passing through fluid or mucus in the small air tubes (bronchioles). Compare RHONCHI. |