major crossmatch

major crossmatch

The testing of a recipient’s serum against potential donor red cells to detect ABO incompatibility and other major antibodies.

crossmatch

Serologic crossmatch Transfusion medicine An agglutination test that determines donor-recipient blood compatibility. See Electronic crossmatch, Immediate spin crossmatch, Major crossmatch, Minor crossmatch. Crossmatch Major crossmatch Patient serum–which may contain antibodies is cross-reacted against the donor's red cells and Minor crossmatch Patient RBCs are incubated with donor serum, this is of less clinical significance; it reveals donor antibodies against uncommon antigens–eg Cw, -Wra, -Lia