| Acronym | Definition |
|---|
| MC2➣Mass Communication Specialist 2nd Class (US Navy) |
| MC2➣Midnight Club 2 (gaming) |
| MC2➣Mesoscale Compressible Community (meteorology model) |
| MC2➣Mech Commander 2 (computer game) |
| MC2➣Management Computer Controls, Inc |
| MC2➣Model of Colloidal Computing |
| MC2➣Mixed Cryoglobulinemia Type 2 |