ABC transporter proteins

ABC transporter proteins

a superfamily of carrier proteins that bind two highly conserved ATP-binding cassettes and function in transporting peptides, sugars, polysaccharides, and ions across the cell membrane. Mutations in the gene that codes for one of these ABC transporter proteins is believed to be responsible for cystic fibrosis.
See also: cystic fibrosis, carrier protein.
[ATP-binding cassette]

ABC transporter proteins

A large and diverse family of cell membrane transport proteins with two transmembrane domains and two ATP-binding regions within the cytosol. The transmembrane domains provide a controllable pathway for transported substance to pass through the cell membrane into or out of the cell.