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单词 mineralocorticoids
释义

mineralocorticoids


mineralocorticoids

Hormones (e.g., aldosterone) produced by the adrenal cortex. They help to regulate mineral metabolism and the level of fluid in the body.

Mineralocorticoids


Mineralocorticoids

 

hormones of the adrenal cortex that belong to the corticosteroid group and affect mainly the exchange of Na+ and K+ ions in an organism. Human adrenal glands secrete 0.15–0.4 mg daily of aldosterone, the principal mineralocorticoid. Another mineralocorticoid, desoxycorticosterone, is an intermediate product of the biosynthesis of corticosterone and possibly of aldosterone. Mineralocorticosteroids regulate the elimination of electrolytes by the kidneys, thereby promoting the reabsorption of Na+ by the renal tubules and reducing the reabsorption of K+.

An excess of mineralocorticosteroids leads to an increase of Na+ in the blood, which causes water retention and edema. An insufficiency of mineralocorticosteroids leads to the increased elimination of Na+ with the urine, causing increased excretion of water and tissue dehydration.

REFERENCES

Bersin, T. Biokhimiia gormonov. Moscow, 1964. (Translated from German.)
Glaz, E., and P. Vecsei. Aldosterone. Oxford, 1971.

mineralocorticoids


mineralocorticoids

Hormones from the outer layer (cortex) of the adrenal gland that promote retention of sodium and excretion of potassium in the urine. ALDOSTERONE is the most powerful mineralocorticoid. Compare GLUCOCORTICOIDS.

mineralocorticoids

see ADRENAL CORTICAL HORMONES.
ThesaurusSeemineralocorticoid
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