| Acronym | Definition |
|---|
| LESL➣Law Enforcement Standards Laboratory |
| LESL➣Lake Erie Soccer League (Ohio) |
| LESL➣Lietuvos Elektroninio Sporto Lygos (Lithuanian: Lithuanian Electronic Sports League) |
| LESL➣Legend Expert Systems Limited |
| LESL➣Lower Esophageal Sphincter Length (gastroesophageal reflux) |