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Leishman-Donovan bodies
Leishman-Donovan bodies[′lēsh·mən ′dän·ə·vən ‚bäd·ēz] (pathology) Small, oval protozoans lacking flagella and undulating membranes, found within macrophages of the skin, liver, and spleen in leishmanial infections such as kala-azar and mucocutaneous leishmaniasis. Leishman-Donovan bodies
Leishman-Donovan bodies (lesh'man-don-a-van) [Sir William Boog Leishman, Brit. medical officer, 1865–1926; Charles Donovan, Brit. bacteriologist, 1863–1951] Nonflagellated trypanosomes found within the cytoplasm of cells infected by Leishmania donovani, the pathogen that causes visceral Leishmaniasis. Synonym: amastigoteLeishman-Donovan bodies The form in which Leishmania parasites appear in MACROPHAGE cells in LEISHMANIASIS. They appear as oval, nucleated, non-flagellated structures in the CYTOPLASM of the MACROPHAGES. Also known as amastigotes . (Major-General Sir William Boog Leishman, 1865–1926, English Army pathologist, and Lt Col Charles Donovan, 1863–1951, Irish physician). |