| 释义 |
EncyclopediaSeele bel, joseph achilleLe Bel-van't Hoff rule
Le Bel-van't Hoff rule (lĕ-bel' vahnt-hof'), the number of stereoisomers of an organic compound is 2n, where n represents the number of asymmetric carbon atoms (unless there is an internal plane of symmetry); a corollary of Le Bel and van't Hoff's simultaneously announced conclusions, in 1874, that the most probable orientation of the bonds of a carbon atom linked to four groups or atoms is toward the apexes of a tetrahedron, and that this accounted for all then-known phenomena of molecular asymmetry (which involved a carbon atom bearing four different atoms or groups).
See also: stereoisomerism. Le Bel, Joseph Achille, French chemist, 1847-1930. Le Bel-van't Hoff rule - the number of stereoisomers of an organic compound is 2n where n represents the number of asymmetric carbon atoms unless there is an internal plane of symmetry. |