17-hydroxycorticosteroid

17-hydroxycorticosteroid

Any of the steroid hormones synthesized in the adrenal gland by action of 17-hydroxylase–cortisol, cortisone, 11-deoxycortisol and tetrahydro derivatives; urine excretion of 17-OHCSs is a rough guide of functional status of the adrenal gland and rate of catabolism ↑ in Pregnancy, Cushing's disease, obesity, pancreatitis ↓ in Addison's disease, hypopituitarism Ref range < age 1, 1.4-2.8 µmol/24–US: < 1 mg/24; adult 8.2-27.6 µmol/24–US: 3-11 mg/24