histiocyte

his·ti·o·cyte

H0217400 (hĭs′tē-ə-sīt′)n. A macrophage or dendritic cell that is usually immobile and is found in organs and tissues.

[Greek histion, web, diminutive of histos; see stā- in Indo-European roots + -cyte.]

his′ti·o·cyt′ic (-sĭt′ĭk) adj.

histiocyte

(ˈhɪstɪəˌsaɪt) n (Physiology) physiol a macrophage that occurs in connective tissue[C20: alteration of German histiozyt, from Greek histion a little web, from histos web + -cyte] histiocytic adj

Thesaurus

Noun

histiocyte - a macrophage that is found in connective tissueconnective tissue - tissue of mesodermal origin consisting of e.g. collagen fibroblasts and fatty cells; supports organs and fills spaces between them and forms tendons and ligamentsmacrophage - a large phagocyte; some are fixed and other circulate in the blood stream

histiocyte

[his´te-o-sīt″] macrophage. adj., adj histiocyt´ic.

his·ti·o·cyte

(his'tē-ō-sīt'), A tissue macrophage; the class includes hepatic Kupffer cells, alveolar macrophages, giant cells of granulomas, osteoclasts, and dermal Langerhans cells. These cells derive from precursors that normally reside in bone marrow but migrate through the bloodstream to egress into tissues for final differentiation. Synonym(s): histocyte [histio- + G. kytos, cell]

histiocyte

(hĭs′tē-ə-sīt′)n. A macrophage or dendritic cell that is usually immobile and is found in organs and tissues.

his′ti·o·cyt′ic (-sĭt′ĭk) adj.

macrophage

A nonspecific immune defence cell that interacts with proteins and polysaccharide antigens, internalising and partially degrading them, and/or presenting the antigens to T cells in a major histocompatibility complex (MHC) context. Macrophages are involved in secretion, immune interaction with T and B cells and provide lymphokine receptors; once activated, macrophages are highly microbicidal and tumouricidal, often closely associated with the blood vessels, epithelium and mesothelium, which are appropriate sites for non-specific immunocytes.

Morphology
Large (15–80 µm in diameter), often with bleb-like or filiform pseudopodia; one (or rarely more) round to oval, occasionally indented nucleus; nuclear membrane is distinct; nuclear chromatin is fine with a reticular pattern; abundant, pale grey-blue, often granulated (coarse azurophilic granules) and vacuolated cytoplasm with phagocytosed material (RBCs, WBCs, platelets, nuclei, bacteria and remnants in native or degraded form).

his·ti·o·cyte

(his'tē-ō-sīt) A macrophage present in connective tissue.
Synonym(s): histocyte. [histio- + G. kytos, cell]

histiocyte

A fixed scavenging cell (phagocyte) found in connective tissue. Histiocytes are also known as reticuloendothelial cells and reticulum cells. A macrophage that does not migrate.

his·ti·o·cyte

(his'tē-ō-sīt) A macrophage in connective tissue. [histio- + G. kytos, cell]

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macrophage

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Words related to histiocyte

noun a macrophage that is found in connective tissue

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