a diuretic drug that prevents sodium absorption in the kidneys and is used to treat hypertension
thiazide in American English
(ˈθaiəˌzaid, -zɪd)
noun
Pharmacology
a member of a class of diuretic substances that inhibit the reabsorption of sodium chloride in the distal convoluted tubule of the kidneys: used principally to treat hypertension
Word origin
[1955–60; thi- + azide]This word is first recorded in the period 1955–60. Other words that entered Englishat around the same time include: backgrounder, geodesic dome, new wave, opioid, software
Examples of 'thiazide' in a sentence
thiazide
Thiazide users without hyponatremia were selected for the control group.
Lii-Jia Yang, Ping-Hsun Wu, Teng-Hui Huang, Ming-Yen Lin, Jer-Chia Tsai 2018, 'Thiazide-associated hyponatremia attenuates the fracture-protective effect of thiazide:A population-based study.', PLoS ONEhttp://europepmc.org/articles/PMC6285977?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
What are the risk factors, symptoms and pathophysiology of thiazide-induced hyponatremia?
Norbert Lameire 2015, 'The management of hyponatremia', Nephrology @ Point of Carehttp://www.pointofcarejournals.com/poc/napoc/the-management-of-hyponatremia. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The strategy prompted high discussion rates and enhanced thiazide-prescribing rates.
Christensen Alan J, Vander Weg Mark W, Williams Monica B, Buzza Colin D, Kaboli PeterJ, Reisinger Heather 2010, 'Part II, Provider perspectives: should patients be activated to request evidence-basedmedicine? a qualitative study of the VA project to implement diuretics (VAPID)', Implementation Sciencehttp://www.implementationscience.com/content/5/1/24. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Controls were identified from a pool of patients from outpatient clinics who were prescribed thiazide during the study period.
Jishana Farhad Abdul Naseer, Li Li Chen, Huey Sywu Gui, Kheng Yong Ong, Mcvin HuaHeng Cheen, Kaysar Mamun 2017, 'A retrospective case-control study evaluating thiazide-induced hyponatraemia-relatedhospitalisation among older Singaporeans', Proceedings of Singapore Healthcarehttps://doi.org/10.1177/2010105816669367. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Serum potassium levels and concurrent use of beta-blockers were identified as unadjusted possible predictors for hospitalisation due to thiazide-induced hyponatraemia.
Jishana Farhad Abdul Naseer, Li Li Chen, Huey Sywu Gui, Kheng Yong Ong, Mcvin HuaHeng Cheen, Kaysar Mamun 2017, 'A retrospective case-control study evaluating thiazide-induced hyponatraemia-relatedhospitalisation among older Singaporeans', Proceedings of Singapore Healthcarehttps://doi.org/10.1177/2010105816669367. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Limiting free water intake and increasing protein intake are often not successful resulting in thiazide avoidance.
Marcel Ruzicka, Brendan McCormick, Peter Magner, Tim Ramsay, Cedric Edwards, Ann Bugeja,Swapnil Hiremath 2018, 'Thiazide diuretic-caused hyponatremia in the elderly hypertensive: will a bottle ofNepro a day keep hyponatremia and the doctor away? Study protocol for a proof-of-conceptfeasibility trial', Pilot and Feasibility Studieshttp://link.springer.com/article/10.1186/s40814-018-0263-y. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Effective medical treatments including thiazide, potassium citrate, acetohydroxamic acid can prevent new stone formation in most patients.
Monika Kusz, Adam Alzubedi, Joanna Popiołek, Michał Konopelko 2018, 'Prevalence, diagnosis and treatment in urolithiasis.', Journal of Education, Health and Sporthttp://www.ojs.ukw.edu.pl/index.php/johs/article/view/6074. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Following these patients up for 5 years showed that thiazide had the most marked increasein switching rate.
Martin C S Wong, Wilson W S Tam, Clement S K Cheung, Ellen L H Tong, Antonio C H Sek,George John, N T Cheung, Bryan P Y Yan, C M Yu, Stephen Leeder, Sian Griffiths 2013, 'Initial antihypertensive prescription and switching: a 5 year cohort study from 250,851patients.', PLoS ONEhttp://europepmc.org/articles/PMC3544913?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Our primary outcome was the proportion of thiazide prescriptions among all prescriptions made for persons started on antihypertensive medication.
Atle Fretheim, Kari Håvelsrud, Graeme MacLennan, Doris Tove Kristoffersen, AndrewD Oxman 2007, 'The effects of mandatory prescribing of thiazides for newly treated, uncomplicatedhypertension: interrupted time-series analysis.', PLoS Medicinehttp://europepmc.org/articles/PMC1904466?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)