relating to, designating, or involving megakaryocytes
Examples of 'megakaryocytic' in a sentence
megakaryocytic
The myeloid and megakaryocytic cell lines usually remain normal.
Dhauna Karam, Sean Swiatkowski, Mamata Ravipati, Bharat Agrawal 2018, 'Aggressive Systemic Mastocytosis in Association with Pure Red Cell Aplasia', Case Reports in Hematologyhttp://dx.doi.org/10.1155/2018/6928571. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These results are supported by data obtained in the different models of megakaryocytic cell lines.
Sara Ortiz-Rivero, Cristina Baquero, Luis Hernández-Cano, Juan José Roldán-Etcheverry,Sara Gutiérrez-Herrero, Cristina Fernández-Infante, Víctor Martín-Granado, EduardoAnguita, José María de Pereda, Almudena Porras, Carmen Guerrero 2018, 'C3G, through its GEF activity, induces megakaryocytic differentiation and proplateletformation', Cell Communication and Signalinghttp://link.springer.com/article/10.1186/s12964-018-0311-5. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, our recent work has demonstrated the down-regulation of this factor during megakaryocytic differentiation.
Divya Singh, Ghanshyam Upadhyay, Ananya Sengupta, Mohammed A Biplob, Shaleen Chakyayil,Tiji George, Shireen Saleque 2016, 'Cooperative Stimulation of Megakaryocytic Differentiation by Gfi1b Gene Targets Kindlin3and Talin1.', PLoS ONEhttp://europepmc.org/articles/PMC5074496?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The blasts suppressed the erythroid population but not the megakaryocytic population.
Khushboo Dewan, Kiran Agarwal 2015, 'Acute Lymphoblastic Leukemia with Normal Platelet Count', Cancer Translational Medicinehttp://www.cancertm.com/article.asp?issn=2395-3977;year=2015;volume=1;issue=5;spage=181;epage=182;aulast=Dewan. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, the exact mechanism by which diosgenin induces megakaryocytic differentiation has not been elucidated.
Lamia Ghezali, Bertrand Liagre, Youness Limami, Jean-Louis Beneytout, David YannickLeger 2014, 'Sonic Hedgehog Activation Is Implicated in Diosgenin-Induced Megakaryocytic Differentiationof Human Erythroleukemia Cells', PLoS ONE10.1371/journal.pone.0095016. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The most important lesions consisted of multifocal to diffuse granulomas, megakaryocytic dysplasia, and medullary aplasia.
Claudia Momo, Ana Paula Prudente Jacintho, Pamela Rodrigues Reina Moreira, DanísioPrado Munari, Gisele Fabrino Machado, Rosemeri de Oliveira Vasconcelos 2014, 'Morphological Changes in the Bone Marrow of the Dogs with Visceral Leishmaniasis',Veterinary Medicine Internationalhttp://dx.doi.org/10.1155/2014/150582. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
An escape from this physiological process may be associated with certain myeloproliferative neoplasms leading to abnormal megakaryocytic proliferation.
Rodolphe Besancenot, Ronan Chaligné, Carole Tonetti, Florence Pasquier, Caroline Marty,Yann Lécluse, William Vainchenker, Stefan N Constantinescu, Stéphane Giraudier 2010, 'A senescence-like cell-cycle arrest occurs during megakaryocytic maturation: implicationsfor physiological and pathological megakaryocytic proliferation.', PLoS Biologyhttp://europepmc.org/articles/PMC2935456?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)