a medication used in the treatment of heart disease
clofibrate in American English
(kloʊˈfaɪˌbreɪt; kloʊˈfɪbˌreɪt)
noun
a drug, C12H15ClO3, taken to reduce the level of lipids, esp. cholesterol, in the blood
clofibrate in American English
(klouˈfaibreit, -ˈfɪbreit)
noun
Pharmacology
a substance, C12H15ClO3, used principally to reduce elevated plasma triglyceride and cholesterol levels
Word origin
[1960–65; clofibr(ic acid) (perh. c(h)lo(ro)-2 + fibr- + -ic) + -ate2]This word is first recorded in the period 1960–65. Other words that entered Englishat around the same time include: deinstitutionalize, disco, pop art, power play, zip code
Examples of 'clofibrate' in a sentence
clofibrate
Samples were divided into clofibrate (n=41) and control (n=32) groups.
Mahmood NouriShadkam, Mohmmad Javad Mohammadi, Khadijeh Nasiriani 2016, 'Evaluation of the Effect of Oral Clofibrate Intake on Neonatal Total Serum Bilirubin:a Randomized Clinical Trial', Iranian Journal of Neonatologyhttp://ijn.mums.ac.ir/article_7647_fb601ef90cf423cf0670fdc88e4d0acf.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In conclusion, clofibrate decreases cardiac remodeling, decreases inflammatory molecules, and partly preserves myocardial diameters.
Luz Ibarra-Lara, María Sánchez-Aguilar, Elizabeth Soria-Castro, Jesús Vargas-Barrón,Francisco J. Roldán, Natalia Pavón, Juan C. Torres-Narváez, Luz G. Cervantes-Pérez,Gustavo Pastelín-Hernández, Alicia Sánchez-Mendoza 2019, 'Clofibrate Treatment Decreases Inflammation and Reverses Myocardial Infarction-InducedRemodelation in a Rodent Experimental Model', Moleculeshttp://www.mdpi.com/1420-3049/24/2/270. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Case group treated with clofibrate and intensive phototherapy, while control group treated only with intensive phototherapy.
Parviz Ayazi, Abolfazl Mahyar, Morteza Habibi, Farzad Ahmadabadi, Amir Javadi 2012, 'The Effect of Clofibrate on Hyperbilirubinemia of Term Neonates', Acta Medica Iranicahttp://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20028.pdf&manuscript_id=20028. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The effect of clofibrate in the prevention of hyperbilirubi-nemia in healthy term neonates has not been paid attention to.
Yadollah Zahed Pasha, Sadroddin Mahdipour, Mousa Ahmadpour-Kacho, Ali Bijani, MaryamTaheri 2015, 'Preventive Effect of Clofibrate on Neonatal Hyperbilirubinemia', Caspian Journal of Pediatricshttp://caspianjp.ir/browse.php?a_code=A-10-27-1&slc_lang=en&sid=1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This study aimed to evaluate the preventive effect of clofibrate on neonatal jaundice in term neonates.
Yadollah Zahed Pasha, Sadroddin Mahdipour, Mousa Ahmadpour-Kacho, Ali Bijani, MaryamTaheri 2015, 'Preventive Effect of Clofibrate on Neonatal Hyperbilirubinemia', Caspian Journal of Pediatricshttp://caspianjp.ir/browse.php?a_code=A-10-27-1&slc_lang=en&sid=1. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The effects of clofibrate on the hemodynamic and renal manifestations of increased saline intake were analyzed.
Antonio Cruz, Isabel Rodríguez-Gómez, Rocío Pérez-Abud, Miguel Ángel Vargas, RosemaryWangensteen, Andrés Quesada, Antonio Osuna, Juan Manuel Moreno 2011, 'Effects of Clofibrate on Salt Loading-Induced Hypertension in Rats', Journal of Biomedicine and Biotechnologyhttp://dx.doi.org/10.1155/2011/469481. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
In conclusion, clofibrate was effective in reducing neonatal jaundice and its effect appeared 24 hours after treatment.
Parviz Ayazi, Abolfazl Mahyar, Morteza Habibi, Farzad Ahmadabadi, Amir Javadi 2012, 'The Effect of Clofibrate on Hyperbilirubinemia of Term Neonates', Acta Medica Iranicahttp://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20028.pdf&manuscript_id=20028. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
This study was conducted to determine the therapeutic effect of clofibrate in term neonates with non-hemolytic jaundice.
Parviz Ayazi, Abolfazl Mahyar, Morteza Habibi, Farzad Ahmadabadi, Amir Javadi 2012, 'The Effect of Clofibrate on Hyperbilirubinemia of Term Neonates', Acta Medica Iranicahttp://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/20028.pdf&manuscript_id=20028. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)