a drug which operates by blocking the production of hydrogen ions and hydrogen carbonate, used to treat various conditions including epilepsy and glaucoma
acetazolamide in American English
(əˌsitəˈzouləˌmaid, -mɪd, -ˈzɑlə-, ˌæsɪtə-)
noun
Pharmacology
a crystalline powder, C4H6N4O3S2, used chiefly in the treatment of glaucoma and edema
Word origin
[1950–55; acet- + azole + amide]This word is first recorded in the period 1950–55. Other words that entered Englishat around the same time include: action painting, conflict of interest, hot line, point-of-sale, wiretap
Examples of 'acetazolamide' in a sentence
acetazolamide
We started the patient on tablet acetazolamide, domperidone, and systemic steroids.
Chandana Chakraborti, Nabanita Barua, Rosy Chishti, Jayitri Mazumdar, Sheuli Kumar 2016, 'Benign intracranial hypertension associated with hypothyroidism in a hemophilic child',Medical Journal of Dr. D.Y. Patil Universityhttp://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=5;spage=642;epage=644;aulast=Chakraborti. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
He was treated with gentamicin, rifampicin, and septrin along with acetazolamide forraised intracranial pressure.
Padam P. Sharma, Mangudi V. Murali, Tahsin Hamdi 2017, 'Neurobrucellosis Presenting as Pseudotumor Cerebri: First Report from Oman', Oman Medical Journalhttp://omjournal.org/articleDetails.aspx?coType=1&aId=2058. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
She presented partial improvement of the headache with acetazolamide, but the visual loss persisted.
Everton Cazzo, Martinho Antonio Gestic, Murillo Pimentel Utrini, Felipe David MendonçaChaim, Fábio Henrique Mendonça Chaim, Elaine Cristina Cândido, Luciana Bueno da SilveiraJarolavsky, Ana Maria Neder de Almeida, José Carlos Pareja, Elinton Adami Chaim 2017, 'Bariatric surgery as a treatment for pseudotumor cerebri: case study and narrativereview of the literature', São Paulo Medical Journalhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802017005007103&lng=en&tlng=en. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
The patient was successfully treated with systemic acetazolamide and topical pilocarpine.
Flavio Mantelli, Solmaz Abdolrahimzadeh, Giuseppe Mannino, Alessandro Lambiase 2014, 'Unusual Case of Angle Closure Glaucoma in a Patient with Neurofibromatosis Type 1',Case Reports in Ophthalmologyhttp://www.karger.com/Article/FullText/369334. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Treatment with medroxyprogesterone, fluoxetine and acetazolamide was also started.
Pedro Schestatsky, Luis Nelson Teixeira Fernandes 2004, 'Acquired Ondine's curse: case report Maldição de Ondina adquirida: relato de caso',Arquivos de Neuro-Psiquiatriahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000300027. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
These results indicated that acetazolamide microsponges in situ gel have potential ability for ophthalmic delivery.
Manar M. Obiedallah, A.M. Abdel-Mageed, Tahani H. Elfaham 2018, 'Ocular administration of acetazolamide microsponges in situ gel formulations', Saudi Pharmaceutical Journalhttp://www.sciencedirect.com/science/article/pii/S1319016418300057. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Use of intravenous steroids may be considered along with acetazolamide.
Rana Al-Senawi, Anuradha Ganesh, Aisha Al-Busaidi, Amna Al-Futaisi, Nassra Al-Habsi,Sana Al-Zuhaibi 2008, 'Visual loss at presentation in children with pseudotumor cerebri', Oman Journal of Ophthalmologyhttp://www.ojoonline.org/article.asp?issn=0974-620X;year=2008;volume=1;issue=1;spage=18;epage=24;aulast=Al-Senawi. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Her neuro-ophthalmological clinical features responded well to acetazolamide and diagnostic/ therapeutic lumbar puncture.
Mandreker Bahall, Antonio Jose Reyes, Kanterpersad Ramcharan, Nadeem Hosein, KaranSeegobin, Krishni Bahall, Hiranyadeva Sharma, Stephanie Dhansingh, Amanda Mahabir 2016, 'Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a formefruste of idiopathic intracranial hypertension?', Neurology Internationalhttp://www.pagepress.org/journals/index.php/ni/article/view/6132. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
We conclude that providers should monitor for pseudotumor cerebri and consider topiramate if acetazolamide fails.
Morgan B. Smith, Elizabeth A. Griffiths, James E. Thompson, Eunice S. Wang, Meir Wetzler,Craig W. Freyer 2014, 'High pseudotumor cerebri incidence in tretinoin and arsenic treated acute promyelocyticleukemia and the role of topiramate after acetazolamide failure', Leukemia Research Reportshttp://www.sciencedirect.com/science/article/pii/S221304891400017X. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Acetazolamide, a carbonic anhydrase inhibitor and atypical antiseizure medication, decreases seizures in four patients.
Jenna Klotz, Brenda E Porter, Claire Colas, Avner Schlessinger, Ana M Pajor 2016, 'Mutations in the Na+/Citrate Cotransporter NaCT (SLC13A5) in Pediatric Patients withEpilepsy and Developmental Delay', Molecular Medicinehttp://link.springer.com/article/10.2119/molmed.2016.00077. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)