Microscopic examination revealed features of extramedullary hematopoiesis.
Basharat Mubeen, Iqbal M Lone, Arif Hameed, Annu Charak, Imza Feroz 2013, 'Extramedullary hematopoiesis presenting as a solitary renal mass and mimicking a malignanttumor: A rare case report', Archives of Medicine and Health Scienceshttp://www.amhsjournal.org/article.asp?issn=2321-4848;year=2013;volume=1;issue=2;spage=159;epage=162;aulast=Mubeen. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
However, its role in normal hematopoiesis and leukaemogenesis remains unclear.
Chao Shen, Ming-Tai Chen, Xin-Hua Zhang, Xiao-Lin Yin, Hong-Mei Ning, Rui Su, Hai-ShuangLin, Li Song, Fang Wang, Yan-Ni Ma, Hua-Lu Zhao, Jia Yu, Jun-Wu Zhang 2016, 'The PU.1-Modulated MicroRNA-22 Is a Regulator of Monocyte/Macrophage Differentiationand Acute Myeloid Leukemia.', PLoS Geneticshttp://europepmc.org/articles/PMC5019412?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Preoperative imaging suggested hamartoma, extramedullary hematopoiesis, or an inflammatory pseudotumor.
Goshi Fujimoto, Ken Hayashi, Shigetoshi Yamada, Hiroshi Kusanagi, Koichi Honma 2018, 'Xanthogranulomatosis of the spleen: a case report', Surgical Case Reportshttp://link.springer.com/article/10.1186/s40792-018-0448-x. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hematopoiesis results in the correct formation of all the different blood cell types.
Alberto Rissone, Shawn M. Burgess 2018, 'Rare Genetic Blood Disease Modeling in Zebrafish', Frontiers in Geneticshttps://www.frontiersin.org/article/10.3389/fgene.2018.00348/full. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
They lack multi-lineage human hematopoiesis and a functional human immune system.
Connick Elizabeth, Palmer Brent E, Wheat William H, Berges Bradford K, Akkina Ramesh 2006, 'HIV-1 infection and CD4 T cell depletion in the humanized Rag2-/-γc-/-(RAG-hu) mouse model', Retrovirologyhttp://www.retrovirology.com/content/3/1/76. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Hence, the white body has been described as the site of hematopoiesis in cephalopods.
Karla A Salazar, Nina R Joffe, Nathalie Dinguirard, Peter Houde, Maria G Castillo 2015, 'Transcriptome analysis of the white body of the squid Euprymna tasmanica with emphasison immune and hematopoietic gene discovery.', PLoS ONEhttp://europepmc.org/articles/PMC4361686?pdf=render. Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Transcriptional factors play important role in hematopoiesis.
Li Peng, Xiao Yiren, Liu Zhixin, Liu Pentao 2012, 'Using mouse models to study function of transcriptional factors in T cell development',Cell Regenerationhttp://www.cellregenerationjournal.com/content/1/1/8. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
Ectopic hematopoiesis was seen in implants after 12 weeks from implantation.
Vasiljević Perica J., Najman Stevo J., Đorđević Ljubiša B., Savić Vojin P., VukelićMarija Đ., Živanov-Čurlis Jelena Z., Ignjatović Nenad L., Uskoković Dragan P. 2009, 'Ectopic osteogenesis and hematopoiesis after implantantion of bone marrow cells seededon HAP/PLLA scaffold', Hemijska Industrijahttp://www.doiserbia.nb.rs/img/doi/0367-598X/2009/0367-598X0904301V.pdf. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)
They regulate immunity, inflammation, cell activation, cell migration, cell proliferation, apoptosis, and hematopoiesis.
Arijit Coondoo 2011, 'Cytokines in dermatology - A basic overview', Indian Journal of Dermatologyhttp://www.e-ijd.org/article.asp?issn=0019-5154;year=2011;volume=56;issue=4;spage=368;epage=374;aulast=Coondoo. Retrieved from DOAJ CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode)