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单词 carboxyl
释义

carboxyln.

Brit. /kɑːˈbɒksʌɪl/, /kɑːˈbɒksɪl/, U.S. /kɑrˈbɑksl/
Origin: Formed within English, by compounding. Etymons: carbo- comb. form, -oxyl comb. form.
Etymology: < carbo- comb. form + -oxyl comb. form.
Chemistry. The radical or group —COOH, present in all fatty (carboxylic) acids. Frequently attributive, as carboxyl group, carboxyl compound.
ΚΠ
1869 H. E. Roscoe Lessons Elem. Chem. (new ed.) xxxii. 322 The acid is a compound of an alcohol radical with the monad group, COHO to which the name of Carboxyl has been given. This substance we thus regard contained in all the fatty acids.
1878 C. T. Kingzett Animal Chem. 33 Hydrogen is replaced by a monad carboxyl group.
1903 Westm. Gaz. 28 Dec. 1/3 By introducing into it a carboxyl two new compounds are formed, from both of which camphor can now be obtained.
1929 R. P. Walton tr. E. Waldschmidt-Leitz Enzyme Actions & Properties 164 For clupein the fraction of carboxyls liberated by trypsin amounts to one-fifth of the total enzymically liberated groups.
1956 E. I. Rabinowitch Photosynthesis II. ii. xxxviii. 1982 The reduction of certain carbonyl and—with the help of high-energy phosphate—also of some carboxyl compounds.
1995 B. Leonard Gloss. HIV/Aids-related Terms 7 When the carboxyl carbon atom of one amino acid binds to the nitrogen of another with the release of a water molecule, a linkage called a peptide bond is formed.
2007 J. D. Watson Avoid boring People xi. 200 He revealed the presence of transfer RNA molecules at the carboxyl ends of growing polypeptide chains.

Compounds

carboxyl-terminal adj. Biochemistry = carboxy-terminal adj. at carboxy- comb. form .
ΚΠ
1952 Bull. Chem. Soc. Japan 25 214/2 When proteins are treated with anhydrous hydrazine..only carboxyl-terminal amino acids are liberated as free amino acids.
1989 B. Alberts et al. Molecular Biol. Cell (ed. 2) xii. 711 (caption) The two Ca2+-binding sites in the carboxyl-terminal part of the molecule have a tenfold higher affinity for Ca2+ than those in the amino-terminal part.
2004 Jrnl. Cell Biol. 167 946/2 Two splice variants..which differ only in carboxyl-terminal residues.
This entry has been updated (OED Third Edition, December 2008; most recently modified version published online December 2021).
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