agammaglobulinaemiaagammaglobulinemian.

Brit.

/ˌeɪɡaməˌɡlɒbjᵿlɪˈniːmɪə/, U.S.

/ˌeɪɡæməˌɡlɑbjᵿlɪˈnimiə/

Forms: 1900s– agammaglobulinaemia, 1900s– agammaglobulinemia.

Origin: Formed within English, by derivation. Etymons: a- prefix⁶, gamma globulin n. at gamma n. and adj. Compounds 2b, -aemia suffix.

Etymology: < a- prefix⁶ + gamma globulin n. at gamma n. and adj. Compounds 2b + -aemia suffix.

Medicine.

Absence or marked reduction of gamma globulin (immunoglobulin) in the blood, typically resulting in impaired immunity; any of various inherited or acquired conditions characterized by this.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > deficiency of other substances

hypinosis1845

anaemotrophy1860

hypoglycaemia1894

hypoleucocytosis1897

acapnia1898

leucopenia1898

hypothyroidism1905

hypocapnia1908

lymphopenia1909

hypoparathyroidism1910

neutropenia1915

thrombopenia1915

thrombocytopenia1921

agranulocytosis1923

hypocalcaemia1925

insulin shock1925

hypochloraemia1927

granulocytopenia1931

hypopotassaemia1932

hypomagnesaemia1933

hypoproteinaemia1934

hyponatraemia1935

hypophosphataemia1935

hypoprothrombinaemia1936

hypoalbuminaemia1937

sideropenia1938

afibrinogenaemia1941

pancytopenia1941

hypokalaemia1949

agammaglobulinaemia1952

hypogammaglobulinaemia1955

haemoglobinopathy1957

1952 O. C. Bruton in Pediatrics 9 722 Agammaglobulinemia. The complete absence of gamma globulin in human serum with a normal total protein..does not appear to have as yet been reported in the literature.

1975 Cellular Immunol. 20 274 We have recently been able to produce agammaglobulinemia in this strain of birds with doses of CY [= cyclophosphamide] much lower than those required for other strains.

1993 Independent 22 Jan. 5/2 Researchers..found the gene for agammaglobulinaemia..by studying 33 families afflicted by the inherited disorder.

2004 J. Playfair Living with Germs ix. 211 One application of passive immunotherapy which is not outdated is the monthly injections of normal human serum to patients with agammaglobulinaemia.

Derivatives

ˌagammaˌglobuliˈnaemic adj. (also agammaglobulinemic) affected with agammaglobulinaemia.

ΘΚΠ

the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adjective] > deficiency of other substances

dispirited1740

hypinotic1855

hypoglycaemic1923

thrombocytopenic1923

thrombopenic1924

neutropenic1932

hypocalcaemic1935

hypoproteinaemic1935

sideropenic1939

hypoprothrombinaemic1942

hypophosphataemic1946

hypopotassaemic1950

hypokalaemic1953

agammaglobulinaemic1954

hyponatraemic1955

hypomagnesaemic1960

1954 Amer. Jrnl. Dis. Children 88 626 (heading) The response of lymph nodes of normal and congenitally agammaglobulinemic children to antigenic stimulation.

1985 Jrnl. Virol. 55 567/1 These piglets were agammaglobulinemic at birth.

2007 Brit. Med. Jrnl. 27 Oct. 881/1 Invasive pneumococcal disease in agammaglobulinaemic patients has declined since the advent of higher dose intravenous gammaglobulin.

This entry has been updated (OED Third Edition, September 2012; most recently modified version published online December 2021).

单词	agammaglobulinaemia
释义	agammaglobulinaemiaagammaglobulinemian. Brit. /ˌeɪɡaməˌɡlɒbjᵿlɪˈniːmɪə/, U.S. /ˌeɪɡæməˌɡlɑbjᵿlɪˈnimiə/ Forms: 1900s– agammaglobulinaemia, 1900s– agammaglobulinemia. Origin: Formed within English, by derivation. Etymons: a- prefix⁶, gamma globulin n. at gamma n. and adj. Compounds 2b, -aemia suffix. Etymology: < a- prefix⁶ + gamma globulin n. at gamma n. and adj. Compounds 2b + -aemia suffix. Medicine. Absence or marked reduction of gamma globulin (immunoglobulin) in the blood, typically resulting in impaired immunity; any of various inherited or acquired conditions characterized by this. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > deficiency of other substances hypinosis1845 anaemotrophy1860 hypoglycaemia1894 hypoleucocytosis1897 acapnia1898 leucopenia1898 hypothyroidism1905 hypocapnia1908 lymphopenia1909 hypoparathyroidism1910 neutropenia1915 thrombopenia1915 thrombocytopenia1921 agranulocytosis1923 hypocalcaemia1925 insulin shock1925 hypochloraemia1927 granulocytopenia1931 hypopotassaemia1932 hypomagnesaemia1933 hypoproteinaemia1934 hyponatraemia1935 hypophosphataemia1935 hypoprothrombinaemia1936 hypoalbuminaemia1937 sideropenia1938 afibrinogenaemia1941 pancytopenia1941 hypokalaemia1949 agammaglobulinaemia1952 hypogammaglobulinaemia1955 haemoglobinopathy1957 1952 O. C. Bruton in Pediatrics 9 722 Agammaglobulinemia. The complete absence of gamma globulin in human serum with a normal total protein..does not appear to have as yet been reported in the literature. 1975 Cellular Immunol. 20 274 We have recently been able to produce agammaglobulinemia in this strain of birds with doses of CY [= cyclophosphamide] much lower than those required for other strains. 1993 Independent 22 Jan. 5/2 Researchers..found the gene for agammaglobulinaemia..by studying 33 families afflicted by the inherited disorder. 2004 J. Playfair Living with Germs ix. 211 One application of passive immunotherapy which is not outdated is the monthly injections of normal human serum to patients with agammaglobulinaemia. Derivatives ˌagammaˌglobuliˈnaemic adj. (also agammaglobulinemic) affected with agammaglobulinaemia. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adjective] > deficiency of other substances dispirited1740 hypinotic1855 hypoglycaemic1923 thrombocytopenic1923 thrombopenic1924 neutropenic1932 hypocalcaemic1935 hypoproteinaemic1935 sideropenic1939 hypoprothrombinaemic1942 hypophosphataemic1946 hypopotassaemic1950 hypokalaemic1953 agammaglobulinaemic1954 hyponatraemic1955 hypomagnesaemic1960 1954 Amer. Jrnl. Dis. Children 88 626 (heading) The response of lymph nodes of normal and congenitally agammaglobulinemic children to antigenic stimulation. 1985 Jrnl. Virol. 55 567/1 These piglets were agammaglobulinemic at birth. 2007 Brit. Med. Jrnl. 27 Oct. 881/1 Invasive pneumococcal disease in agammaglobulinaemic patients has declined since the advent of higher dose intravenous gammaglobulin. This entry has been updated (OED Third Edition, September 2012; most recently modified version published online December 2021). < n.1952
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