Zollinger–Ellison syndromen.
/ˌzɒlᵻndʒə(r)ˈɛlᵻs(ə)n ˌsɪndrəʊm/, U.S. /ˌzɑləndʒərˈɛləsən ˌsɪnˌdroʊm/, /ˌzɑlɪŋɡərˈɛləsən ˌsɪnˌdroʊm/, /ˌzɑləndʒərˈɛləsən ˌsɪndrəm/, /ˌzɑlɪŋɡərˈɛləsən ˌsɪndrəm/ Pathology.
A syndrome characterized by excessive gastric acid secretion (producing recurrent peptic ulcers) associated with a gastrin-secreting tumour or hyperplasia of the islet cells of the pancreas.
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the world > health and disease > ill health > a disease > disorders of internal organs > glandular disorders > [noun] > disorders of pancreas
pancreatitis1842
Zollinger–Ellison syndrome1956
1956 Eiseman & Maynard in Gastroenterology XXXI. 302 For the sake of simplicity we propose this clinical entity be called the Zollinger-Ellison syndrome.
1960 Jrnl. Royal Coll. of Surgeons of Edinb. 5 191 Since that time [sc. 1955] over 100 instances of co-existent peptic ulcer and islet cell tumours have been described and the association appears to constitute a clinical entity called, by general consent, the ‘Zollinger-Ellison syndrome’.
1962 Lancet 12 May 1003/2 The characteristics of the Zollinger–Ellison syndrome are extreme gastric hyper~secretion, intractable peptic ulceration..and either hyperplasia or tumour of the islet-cells of the pancreas.
1974 R. M. Kirk et al. Surgery vi. 85/1 In the Zollinger-Ellison syndrome, ulcers may occur at the duodenojejunal junction.
This entry has not yet been fully updated (first published 1986; most recently modified version published online March 2022).
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n.1956