vincan.1
/ˈvɪŋkə/, U.S. /ˈvɪŋkə/ = periwinkle n.1 1a; vinca alkaloid n. any of several alkaloids (as vinblastine, vincristine) obtained from a periwinkle.
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the world > plants > particular plants > cultivated or valued plants > particular cultivated or ornamental plants > foliage, house, or garden plants > [noun] > periwinkle
sengreenc1000
periwinkleOE
clematis1551
pervenche1845
vinca1868
myrtle1880
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for cancer or leukemia
amethopterin1948
Myleran1952
Laetrile1953
thioguanine1953
thioTEPA1953
mercaptopurine1954
methotrexate1955
busulfan1956
chlorambucil1956
cyclophosphamide1960
vinblastine1962
vincristine1962
levamisole1969
vinca alkaloid1970
doxorubicin1971
tamoxifen1972
Airol1974
trastuzumab1997
thiotepa-
1868 D. Thomson Handy Bk. Flower Garden ix. 250 For forming permanent edgings to large beds, these Vincas are very effective.
1937 A. T. Johnson Woodland Garden vii. 70 The vincas as a tribe are either misused or not used at all.
1961 D. Stuart Driven xvii. 170 There had been pride and delight in her eyes when first the oleanders she tended so carefully had bloomed, and all the outside of the camp was a blaze of vincas that same season.
1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xxix. 11/2 Effects peculiar to the vinca alkaloids..include paraesthesia (especially round the mouth), temporary mental depression, loss of deep tendon reflexes and more rarely headaches, psychoses and convulsions.
1978 R. B. Scott Price's Textbk. Pract. Med. (ed. 12) iv. 374/1 The vinca alkaloids vinblastine (VLB) and vincristine (VCR)..have a variety of toxic effects other than those on dividing cells.
This entry has not yet been fully updated (first published 1986; most recently modified version published online December 2021).
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