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单词 valproate
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valˈproate
valˈproate n. a salt of this acid, esp. the sodium salt, an anticonvulsant drug given orally in cases of epilepsy.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations
Dilantin1938
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mephenesin1952
troxidone1952
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acetazolamide1954
orphenadrine1957
tetrabenazine1958
ethosuximide1960
methsuximide1965
clonazepam1970
valproic1972
valproate1974
1974 Brit. Med. Jrnl. 15 June 584/1 The anticonvulsant effects of sodium dipropylacetate (sodium valproate) were first reported in France.
1983 F. E. Dreifuss in Pedley & Meldrum Rec. Adv. in Epilepsy I. iii. 35 Clinical experience with Valproate extends over nearly 20 years.
1983 F. E. Dreifuss in Pedley & Meldrum Rec. Adv. in Epilepsy I. iii. 35 The term Valproate is used here to refer both to valproic acid and its salts (sodium or magnesium).
extracted from valproicadj.
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