tryparsamiden.

/trɪˈpɑːsəmʌɪd/

Etymology: < tryp- (in Trypanosoma n.) + -ars- (in arsenic n.) + amide n.

Pharmacology.

An arsenical organic compound, C₈H₁₀AsN₂NaO₄.½H₂O, used to treat trypanosomiasis and syphilis of the central nervous system.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > other internal parasiticides > specific drugs

phenanthridine1890

trypan red1905

trypan blue1911

tryparsamide1921

Bayer 2051922

stibophen1941

stilbamidine1941

suramin1941

mepacrine1943

PABA1943

metronidazole1960

stibocaptate1962

1921 Jrnl. Exper. Med. 33 193 (heading) Therapeutic action of N-phenylglycineamide-p-arsonic acid (tryparsamide) upon experimental infections of Trypanosoma rhodesiense.

1935 Lancet 26 Jan. 193/2 After one injection of reduced tryparsamide the trypanocidal titre of the urine rapidly rose to an enormous level.

1974 Trypanosomiasis & Leishmaniasis: Ciba Found. Symp. 1973 310 The problem of drug resistance has became of less importance since the discontinuance of tryparsamide for the treatment of established cases, and its replacement by melaminyl derivatives of arsenic such as melarsoprol and melarsonyl potassium.

This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).

单词	tryparsamide
释义	tryparsamiden. /trɪˈpɑːsəmʌɪd/ Etymology: < tryp- (in Trypanosoma n.) + -ars- (in arsenic n.) + amide n. Pharmacology. An arsenical organic compound, C₈H₁₀AsN₂NaO₄.½H₂O, used to treat trypanosomiasis and syphilis of the central nervous system. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > other internal parasiticides > specific drugs phenanthridine1890 trypan red1905 trypan blue1911 tryparsamide1921 Bayer 2051922 stibophen1941 stilbamidine1941 suramin1941 mepacrine1943 PABA1943 metronidazole1960 stibocaptate1962 1921 Jrnl. Exper. Med. 33 193 (heading) Therapeutic action of N-phenylglycineamide-p-arsonic acid (tryparsamide) upon experimental infections of Trypanosoma rhodesiense. 1935 Lancet 26 Jan. 193/2 After one injection of reduced tryparsamide the trypanocidal titre of the urine rapidly rose to an enormous level. 1974 Trypanosomiasis & Leishmaniasis: Ciba Found. Symp. 1973 310 The problem of drug resistance has became of less importance since the discontinuance of tryparsamide for the treatment of established cases, and its replacement by melaminyl derivatives of arsenic such as melarsoprol and melarsonyl potassium. This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018). < n.1921
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