toxoidn.
/ˈtɒksɔɪd/ A modification or transformation product of a toxin, in which the toxophoric group of atoms is lost, and which has therefore no toxic effect, but retains affinity for the antitoxin. Also attributive.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > prophylactic medicine > [noun]
preservativec1425
preservationc1475
prophylactic?1541
preserve1554
preservatory1654
preventive1666
preventative1699
phylactic1711
toxoid1900
1900 Lancet 18 Aug. 528/1 Very sensitive animals such as mice and guinea-pigs might..be easily and rapidily immunised against tetanus by means of toxoids only.
1902 Brit. Med. Jrnl. 29 Mar. 785 The modified toxin consists of a molecule with a haptophoric but no toxophoric group and is called ‘toxoid’.
1903 Brit. Med. Jrnl. 21 Mar. 654 The toxoids may again be subdivided into three groups, according to their affinity for the antitoxin, which may obviously be either greater (protoxoid), equal (syntoxoid), or less than (epitoxoid) that of the toxin.
1904 Brit. Med. Jrnl. 10 Sept. 577 They were however able to produce toxoid formation in this constituent.
This entry has not yet been fully updated (first published 1913; most recently modified version published online September 2018).
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n.1900