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thiouracil
thiouracil n. 
/ˌθʌɪə(ʊ)ˈjɔːrəsɪl/,
Brit. /ˌθʌɪə(ʊ)ˈjʊərəsɪl/
, /ˌθʌɪə(ʊ)ˈjʊərəsɪl//ˌθʌɪə(ʊ)ˈjɔːrəsɪl/U.S. /ˌθaɪoʊˈjʊrəˌsɪl/
a mercapto derivative of uracil that has been used to depress the activity of the thyroid gland; 4-hydroxy-2-mercaptopyrimidine, C4H4N2OS./ˌθaɪoʊˈjʊrəˌsɪl/ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for thyroid conditions
thyro-antitoxin1895
thiouracil1905
propylthiouracil1914
methylthiouracil1944
methimazole1951
thiamazole1971
1905 Wheeler & Bristol in Amer. Chem. Jrnl. 33 458 2-Thiouracil... This compound was first obtained.. when pseudoethylthiourea, containing some thiourea, was condensed with ethyl sodium formylacetate.
1977 Martindale's Extra Pharmacopœia (ed. 27) 304/1 Thiouracil was formerly used in the control and treatment of thyrotoxicosis and in the preparation of patients for thyroidectomy.
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