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单词 site-directed
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site-directed
site-directed adj. Molecular Biology designating a method for creating a mutation in a specific nucleic acid sequence; (also) designating an organism having such a mutation or the mutation itself.
ΚΠ
1974 R. A. Flavell et al. in Jrnl. Molecular Biol. 89 255 (title) Site-directed mutagenesis: generation of an extracistronic mutation in bacteriophage Qβ RNA.
1989 BioFactors 2 14/1 Site-directed mutants of the EGF receptor have provided valuable information.
1993 National Acad. Keck Futures Initiative Genomic Revol. 30 In this case, researchers would also engineer site-directed mutations in potentially pandemic flu viruses..and evaluate how virulence and pathogenicity are affected.
2015 B. H. Lee Fund. Food Biotechnol. (ed. 2) ii. v. 327 Eventually site-directed mutagenesis will replace tedious traditional mutation procedures, but this technique requires recombinant DNA technology and also needs detailed knowledge of the three-dimensional structure of the enzyme.
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