α. 1800s serin.
β. 1800s– serine.
serinen.1
/ˈsɪəriːn/, /ˈsɪərɪn/, /ˈsɛriːn/, /ˈsɛrɪn/, U.S. /ˈsɛˌrin/, /ˈsɛrən/ 1. The soluble protein present in blood serum; = serum albumin at serum n. Compounds 1a. Now historical.
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1859 Brit. & Foreign Medico-chirurg. Rev. 23 226 Denis admits only five representatives of the albuminous substances..in plants, glutin (gluten), in animals, albumin (of eggs), and serin (albumin of serum), casein, fibrin, and globulin.
1871 H. Watts tr. L. Gmelin Hand-bk. Chem. XVIII. 271 The serin of Denis, which Hoppe-Seyler..regards as serum albumin, seems rather to belong to this place.
1891 W. D. Halliburton Text-bk. Chem. Physiol. 243 The proteids, which were not precipitated by the salt, he called serine, or, as we now call them, serum-albumin.
1972 J. S. Fruton Molecules & Life 121 From the work of Denis and of those who followed him came the separation of a material soluble in water (serum albumin, which Denis termed ‘serine’) from material soluble in dilute salt solutions but insoluble in water.
2. Powdered milk formed by evaporating whey or a mixture of whey and skimmed milk. Now disused.
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the world > food and drink > food > dairy produce > [noun] > milk > whey powder
serine1893
1893 J. P. Dowling & F. McCaffrey Pract. Dairying for Austral. 133 A food stuff named serin is manufactured by evaporating skim-milk and whey together in different proportions for different purposes.
1898 H. Johansen in Windsor Mag. Sept. 436/2 ‘Serin’, or whey powder... This is really nothing else than pulverised whey, which we mixed with boiling water.
1904 N. Engstrōm in G. Sundbärg Sweden ii. vi. 581 W. Rehnstrōm has laboured with great assiduity to produce certain preparations, such as serine and lactoserine, by an evaporation of whey or mixtures of whey and skimmed milk.
This entry has been updated (OED Third Edition, March 2013; most recently modified version published online March 2022).
serinen.2
/ˈsɪəriːn/, /ˈsɪərɪn/, /ˈsɛriːn/, /ˈsɛrɪn/, U.S. /ˈsɛˌrin/, /ˈsɛrən/α. 1800s– serin.
β. 1800s– serine.
Biochemistry.
A hydrophilic amino acid which is a constituent of most proteins. Also as a count noun: a residue of this compound as a constituent of a peptide or protein. Abbreviated Ser.Serine is 2-amino-3-hydroxypropanoic acid, CH2(OH)CH(NH2)COOH. Sometimes with modifying letter distinguishing its two optical isomers: the l-form is found in proteins and the d-form is synthesized in the brain.
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the world > matter > chemistry > organic chemistry > organic compounds > [noun] > amino acids
alanine1850
serine1870
amino-acid1887
histidine1896
canavanine1932
Glu1937
Gly1937
Ala1945
Asp1945
alliin1947
Asn1957
Asx1957
Glx1958
Gln1961
1870 Proc. Royal Soc. Edinb. 7 386/1 Serin, when treated with nitrous acid, yields glyceric acid, as alanine under the same circumstances yields lactic acid, and therefore..may be looked upon as amido-glyceric acid.
1871 H. Watts tr. L. Gmelin Hand-bk. Chem. XVIII. 368 The serine is dissolved in cold water, and filtered from undissolved tyrosine.
1880 Jrnl. Chem. Soc. 38 713 Cramer's..serine is isomeric with amidohydroxypropionic acid.
1908 W. T. Hall & G. Defren tr. E. Abderhalden Text-bk. Physiol. Chem. viii. 149 Serine as it occurs in nature is lævo-rotatory.
1951 Physiol. Zool. 24 351/2 D-serine is extremely toxic to Drosophila; L-serine is slightly toxic under most circumstances.
1991 G. W. Patterson & W. D. Nes Physiol. & Biochem. Sterols i. 18 The protein consists of 121 amino acids with a serine at the N-terminus.
2009 W. G. Hopkins & N. P. A. Hüner Introd. Plant Physiol. (ed. 4) viii. 144/2 There is also the possibility that some of the intermediates, serine and glycine, for example, are of use in other biosynthetic pathways.
Compounds
attributive, in the names of enzymes which catalyse reactions of serine or serine residues, or reactions yielding serine.
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1938 Biochem. Jrnl. 32 403 The decay of dl-serine deaminase appears to be due to a loss from the cell by diffusion of some substance or substances acting as coenzyme.
1943 Jrnl. Biol. Chem. 150 262 The desulfurase and serine dehydrase of mammalian tissue were found to be similar to those of the microorganisms.
1956 Jrnl. Biol. Chem. 220 775 Since the reaction we have studied mainly is the formation of serine, and because of the similarity to aldol type reactions, we propose the name serine aldolase for this enzyme system.
1974 Sci. Amer. July 74/2 Serine proteases participate in digestion, in the formation and dissolution of blood clots, in the immune reaction to foreign cells and organisms, in the fertilization of the ovum by the spermatozoon.
2005 Theriogenology 63 1667 This study examined proteolytic enzymes and serine proteinase inhibitors in turkey seminal plasma.
This entry has been updated (OED Third Edition, March 2013; most recently modified version published online March 2022).
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