self-antigenn.
/ˌsɛlfˈantᵻdʒ(ə)n/, U.S. /ˌsɛlfˈæn(t)ədʒən/, /ˌsɛlfˈæn(t)əˌdʒɛn/ Immunology.
An antigen that is (or is derived from) a constituent of an individual's own body, and hence does not usually elicit an immune response in that individual. Cf. autoantigen n. (b) at auto- comb. form1 1a.
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the world > life > biology > substance > process stimulators or inhibitors > immunogen or antigen > [noun] > types of
precipitogen1904
precipitinogen1907
coccidioidin1931
self-antigen1959
xenoantigen1975
1957 Brit. Med. Jrnl. 28 Sept. 731/2 Connective tissue itself, or the products of its partial breakdown, might under certain circumstances be able to combine with foreign prosthetic groups to form ‘not self’ antigens.]
1959 F. M. Burnet Clonal Select. Theory Acquired Immunity Index 208/2 Self-antigens, lack of response to.
2011 A. J. Czaja in S. P. S. Monga Molecular Pathol. Liver Dis. xli. 623/1 Autoimmune hepatitis is the result of an immune response that is misdirected against normal self-antigens or foreign antigens that resemble self-antigens.
This entry has been updated (OED Third Edition, January 2018; most recently modified version published online March 2022).
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n.1959