adenylatingn.
/əˈdɛnᵻleɪtɪŋ/, U.S. /əˈdɛnəˌleɪdɪŋ/ Biochemistry.
The action or process of adenylating a compound or molecule; adenylation.
ΚΠ
1972 V. Krčméry et al. in First Internat. Symp. Infectious Antibiotic Resistance 19 Biochemical mechanism of plasmid-mediated Gentamycin resistance has been shown to be an adenylating process.
1977 Biochemistry 16 2570/2 Coupling between ligands..has been observed within the adenylating site of several aminoacyl-t RNA synthetases.
1998 D. C. Gross et al. in K. Kohmoto & O. C. Yoder Molecular Genetics Host-specific Toxins Plant Dis. 94 The first amino acid adenylating domain of SypA shared about 51% identity to the corresponding domain of SyrE.
This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021).
adenylatingadj.
/əˈdɛnᵻleɪtɪŋ/, U.S. /əˈdɛnəˌleɪdɪŋ/ Biochemistry.
Of an enzyme, group, etc.: that causes the introduction of an adenyl radical into a compound or molecule.
ΚΠ
1963 B. Pullman & A. Pullman Quantum Biochem. ii. vii. 349 ATP may act either as a phosphorylating agent, a pyrophosphorylating agent or an adenylating agent.
1988 Q. N. Myrvik & R. S. Weiser Fund. Med. Bacteriol. & Mycol. (ed. 2) vi. 87 A variety of enzymes which inactivate aminoglycosides have been identified. These include acetylating, phosphorylating and adenylating enzymes.
2008 C. C. Aldrich & R. V. Somu in P. Herdewijn Modified Nucleosides xiv. 371 The acceptor residue for aryl adenylating enzymes is the terminal sulfur atom of the phosphopantetheinyl cofactor of the carrier domain.
This entry has been updated (OED Third Edition, December 2011; most recently modified version published online December 2021).
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n.1972adj.1963