单词 | raloxifene |
释义 | raloxifenen. Pharmacology. A drug that is a selective oestrogen receptor modulator (stimulating oestrogen receptors in bone and blocking those in the breast and uterus), used chiefly in the treatment of osteoporosis.Chemical name: [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl] [4-(2-piperidinoethoxy)phenyl]methanone, C28H27NO4S. ΚΠ 1985 WHO Chron. 39 iv. Suppl. 16 Raloxifene... 6-hydroxy-2-(p-hydroxyphenyl)benzo[b]thien-3-yl p-(2-piperidinoethoxy)-phenyl ketone. 1993 Prostate 23 245 The benzothiophene anti-estrogen, raloxifene...has selective estrogen pharmacological antagonist activity in female rats. 1998 Syracuse (N.Y.) Herald-Jrnl. 22 Oct. a4/3 The new drug will compare tamoxifen with the osteoporosis drug raloxifen to see if raloxifen will prevent breast cancer with fewer side effects. 2005 Elevate New Year 83/1 Dr. Lawrence and her team..at the University of Ottawa have determined that the anti-estrogen drugs tamoxifen and raloxifene can be used to treat persistent pubertal gynecomastia. This is a new entry (OED Third Edition, June 2008; most recently modified version published online March 2022). < n.1985 |
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