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单词 protomer
释义

protomern.1

Brit. /ˈprəʊtəmə/, U.S. /ˈproʊdəmər/
Origin: Formed within English, by compounding. Etymons: proton n., prototropy n., -mer comb. form2.
Etymology: < proto- (in proton n. or prototropy n.) + -mer comb. form2.
Chemistry.
Each of a number of tautomeric molecules which differ from each other only in the position of a proton; a prototropic tautomer.
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the world > matter > chemistry > isomerism > [noun] > structural isomerism > tautomerism > tautomer > types of
protomer1923
1923 T. M. Lowry in Jrnl. Chem. Soc. 123 828 Prototropy, or the reversible change of protomers, which differ from one another in the position of a proton or hydrogen nucleus.
1979 C. Roussel et al. in J. V. Metzger Thiazole & its Derivatives ii. vii. 379 Protic solvents stabilize more the form giving the stronger hydrogen bond: so the mercapto protomer..should become apparent in the ultraviolet spectra recorded in ethanol.
2005 Jrnl. Amer. Soc. Mass Spectrometry 16 518/2 The simplest explanation for the difference between these ions is that they are protomers of protonated pyrimidinol.
This entry has been updated (OED Third Edition, September 2007; most recently modified version published online March 2022).

protomern.2

Brit. /ˈprəʊtəmə/, U.S. /ˈproʊdəmər/
Origin: Formed within English, by compounding. Etymons: protein n., -o- connective, -mer comb. form2.
Etymology: < prot- (in protein n.) + -o- connective + -mer comb. form2.
Biochemistry.
Each of the protein subunits of which an oligomeric protein is built up.
ΚΠ
1965 J. Monod et al. in Jrnl. Molecular Biol. 12 89 The identical subunits associated within an oligomeric protein are designated as protomers.
1980 Biophysical Chem. 11 49/1 The treatment has been extended to include aggregated structures containing from two to five protomers, thus encompassing almost the whole spectrum of oligomeric proteins likely to be encountered.
1999 E. J. Hoffman Cancer & Search for Selective Biochem. Inhibitors vii. 292 They [sc. enteroviruses] are built up from 60 protomers, and replication takes place in the cytoplasm... Each protomer consists of a single molecule composed of four polypeptides.
This entry has been updated (OED Third Edition, September 2007; most recently modified version published online March 2022).
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