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单词 pseudogene
释义

> as lemmas

pseudogene
pseudogene n.
Brit. /ˈs(j)uːdə(ʊ)dʒiːn/
,
U.S. /ˈsudoʊˌdʒin/
Genetics a DNA sequence that is very similar to that of a functional gene but is not transcribed or translated, e.g. as a result of mutations that have occurred in it.
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satellite1921
trabant1926
secondary constriction1932
puff1936
microsatellite1962
pseudogene1977
1977 C. Jacq et al. in Cell 12 109/1 The 5S DNA of Xenopus laevis, coding for oocyte-type 5S RNA, consists of many copies of a tandemly repeated unit of about 700 base pairs. Each unit contains a ‘pseudogene’ in addition to the gene. The pseudogene has been partly sequenced and appears to be an almost perfect repeat of 101 residues of the gene.
1989 A. J. Jeffreys in J. R. Durant Human Origins iii. 30 Some pseudogenes arise by gene duplication followed by silencing of one of the duplicated genes.
2003 Nature 1 May p. ix The human genome contains 20,000 pseudogenes that do not produce a functional full-length protein.
extracted from pseudo-comb. form
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as lemmas
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