progestinn.

Brit.

/prəʊˈdʒɛstɪn/, U.S.

/proʊˈdʒɛstɪn/

Origin: Formed within English, by derivation. Etymons: progestational adj., -in suffix¹.

Etymology: < progest- (in progestational adj.) + -in suffix¹. Compare German Progestin (W. M. Allen et al. 1935, in Klin. Wochenschr. 17 Aug. 1182/1: see progesterone n.).

Physiology.

Originally: the hormone produced by the corpus luteum; = progesterone n. In later use: = progestogen n.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medical preparations of specific origin > hormones and substances with same effect > [noun]

epinephrine1899

pituitrin1909

oxytocin1927

Pitocin1929

Pitressin1929

progestin1930

progesterone1935

methyltestosterone1936

pregnenolone1936

hexœstrol1939

stilboestrol1939

hydroxyprogesterone1941

progestogen1941

Premarin1942

hydroxycorticosterone1943

gestagen1948

hydrocortisone1951

cortisol1953

fluorohydrocortisone1954

isophane1954

prednisolone1955

prednisone1955

norethisterone1956

norethynodrel1957

dexamethasone1958

fludrocortisone1958

norethindrone1960

antidiuretic hormone1961

medroxyprogesterone1962

Pergonal1963

mesterolone1965

norgestrel1966

quinestrol1966

pancuronium1967

pentagastrin1967

levonorgestrel1977

1930 W. M. Allen in Amer. Jrnl. Physiol. 92 174 We have as yet proposed no name for this hormone of the corpus luteum... In so far as we are acquainted with its physiological behavior, its chief action lies in its ability, by alteration of the endometrium, to aid gestation in the castrated rabbit; and for this reason we wish to propose for it the name progestin, i.e., a substance which favors gestation.

1935 W. M. Allen et al. in Nature 24 Aug. 303/2 Heretofore, two different names have been used in the literature for this hormone (progestin, luteosterone). For the sake of international uniformity, we agree to use..the name progesterone for the pure hormone.

1945 H. Burrows Biol. Actions Sex Hormones xxi. 389 More than one substance having the same kind of action as progesterone is known, and a generic name is therefore convenient. The author has used the term ‘progestin’ to denote chemical compounds having a biological action comparable with that of progesterone. [Note] ‘Progestogen’ has been suggested as an alternative generic name.

1966 New Scientist 15 Dec. 620/1 The synthetic progestins which are contained in all oral contraceptive tablets were in fact introduced for the wrong reason.

1995 Herizons (Winnipeg) Winter 24/3 Progestins also have negative side effects. Commonly, women complain of PMS-like symptoms including breast tenderness, bloating, mood swings and depression.

This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).

单词	progestin
释义	progestinn. Brit. /prəʊˈdʒɛstɪn/, U.S. /proʊˈdʒɛstɪn/ Origin: Formed within English, by derivation. Etymons: progestational adj., -in suffix¹. Etymology: < progest- (in progestational adj.) + -in suffix¹. Compare German Progestin (W. M. Allen et al. 1935, in Klin. Wochenschr. 17 Aug. 1182/1: see progesterone n.). Physiology. Originally: the hormone produced by the corpus luteum; = progesterone n. In later use: = progestogen n. ΘΚΠ the world > health and disease > healing > medicines or physic > medical preparations of specific origin > hormones and substances with same effect > [noun] epinephrine1899 pituitrin1909 oxytocin1927 Pitocin1929 Pitressin1929 progestin1930 progesterone1935 methyltestosterone1936 pregnenolone1936 hexœstrol1939 stilboestrol1939 hydroxyprogesterone1941 progestogen1941 Premarin1942 hydroxycorticosterone1943 gestagen1948 hydrocortisone1951 cortisol1953 fluorohydrocortisone1954 isophane1954 prednisolone1955 prednisone1955 norethisterone1956 norethynodrel1957 dexamethasone1958 fludrocortisone1958 norethindrone1960 antidiuretic hormone1961 medroxyprogesterone1962 Pergonal1963 mesterolone1965 norgestrel1966 quinestrol1966 pancuronium1967 pentagastrin1967 levonorgestrel1977 1930 W. M. Allen in Amer. Jrnl. Physiol. 92 174 We have as yet proposed no name for this hormone of the corpus luteum... In so far as we are acquainted with its physiological behavior, its chief action lies in its ability, by alteration of the endometrium, to aid gestation in the castrated rabbit; and for this reason we wish to propose for it the name progestin, i.e., a substance which favors gestation. 1935 W. M. Allen et al. in Nature 24 Aug. 303/2 Heretofore, two different names have been used in the literature for this hormone (progestin, luteosterone). For the sake of international uniformity, we agree to use..the name progesterone for the pure hormone. 1945 H. Burrows Biol. Actions Sex Hormones xxi. 389 More than one substance having the same kind of action as progesterone is known, and a generic name is therefore convenient. The author has used the term ‘progestin’ to denote chemical compounds having a biological action comparable with that of progesterone. [Note] ‘Progestogen’ has been suggested as an alternative generic name. 1966 New Scientist 15 Dec. 620/1 The synthetic progestins which are contained in all oral contraceptive tablets were in fact introduced for the wrong reason. 1995 Herizons (Winnipeg) Winter 24/3 Progestins also have negative side effects. Commonly, women complain of PMS-like symptoms including breast tenderness, bloating, mood swings and depression. This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022). < n.1930
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