probandn.

Brit.

/ˈprəʊband/,

/ˈprəʊbənd/, U.S.

/ˈproʊˌbænd/

Origin: Apparently a borrowing from German. Etymon: German Proband.

Etymology: Apparently < German Proband examinee, test subject, also used in genealogy and human genetics for a person providing a point of reference (1923 in the passage translated in quot. 1931) < classical Latin probandus that must be proved or demonstrated, worthy of praise or approval, use as adjective of gerundive of probāre prove v. Compare classical Latin probandum something worthy of praise or approval, use as noun of neuter of probandus.

Medicine and Genetics.

The individual with whom the investigation of a family for a genetic disorder or other inherited trait begins; the first member of a family to be diagnosed with a hereditary disease or trait. Cf. propositus n. 3.

ΘΚΠ

the world > life > biology > laboratory analysis > material > [noun] > individual studied for inherited trait

propositus1924

proband1929

proposita1956

1929 Resumptio Genetica IV. Index 296/1 Proband.

1931 E. Paul & C. Paul tr. E. Baur Human Heredity xi. 501 A graphic representation of the parents, grandparents, great-grandparents, etc., of the individual from whom an investigation starts (such a person is called a proband) is known as that person's ancestral table.

1967 Economist 9 Dec. 1065/4 It is said that the Proband test effectively screens disease carriers in an endemic herd, and that once foreign buyers got used to it they would still want British pedigree animals.

1977 Jrnl. Med. Genetics 14 125/2 The same balanced translocation was found in the proband's sister.

1999 New Scientist 26 June 89/1 (advt.) The Diabetes in Families study is a large scale study of siblings of Type 2 diabetic probands.

This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).

单词	proband
释义	probandn. Brit. /ˈprəʊband/, /ˈprəʊbənd/, U.S. /ˈproʊˌbænd/ Origin: Apparently a borrowing from German. Etymon: German Proband. Etymology: Apparently < German Proband examinee, test subject, also used in genealogy and human genetics for a person providing a point of reference (1923 in the passage translated in quot. 1931) < classical Latin probandus that must be proved or demonstrated, worthy of praise or approval, use as adjective of gerundive of probāre prove v. Compare classical Latin probandum something worthy of praise or approval, use as noun of neuter of probandus. Medicine and Genetics. The individual with whom the investigation of a family for a genetic disorder or other inherited trait begins; the first member of a family to be diagnosed with a hereditary disease or trait. Cf. propositus n. 3. ΘΚΠ the world > life > biology > laboratory analysis > material > [noun] > individual studied for inherited trait propositus1924 proband1929 proposita1956 1929 Resumptio Genetica IV. Index 296/1 Proband. 1931 E. Paul & C. Paul tr. E. Baur Human Heredity xi. 501 A graphic representation of the parents, grandparents, great-grandparents, etc., of the individual from whom an investigation starts (such a person is called a proband) is known as that person's ancestral table. 1967 Economist 9 Dec. 1065/4 It is said that the Proband test effectively screens disease carriers in an endemic herd, and that once foreign buyers got used to it they would still want British pedigree animals. 1977 Jrnl. Med. Genetics 14 125/2 The same balanced translocation was found in the proband's sister. 1999 New Scientist 26 June 89/1 (advt.) The Diabetes in Families study is a large scale study of siblings of Type 2 diabetic probands. This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022). < n.1929
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