prednisolonen.
/prɛdˈnɪsələʊn/, U.S. /prɛdˈnɪzəˌloʊn/ Pharmacology.
A synthetic corticosteroid with predominantly glucocorticoid activity, used chiefly as an immunosuppressant and anti-inflammatory agent. Cf. prednisone n.Chemical name: 1,4-pregnadiene-3,20-dione-11β,17α,21-triol; C21H28O5.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medical preparations of specific origin > hormones and substances with same effect > [noun]
epinephrine1899
pituitrin1909
oxytocin1927
Pitocin1929
Pitressin1929
progestin1930
progesterone1935
methyltestosterone1936
pregnenolone1936
hexœstrol1939
stilboestrol1939
hydroxyprogesterone1941
progestogen1941
Premarin1942
hydroxycorticosterone1943
gestagen1948
hydrocortisone1951
cortisol1953
fluorohydrocortisone1954
isophane1954
prednisolone1955
prednisone1955
norethisterone1956
norethynodrel1957
dexamethasone1958
fludrocortisone1958
norethindrone1960
antidiuretic hormone1961
medroxyprogesterone1962
Pergonal1963
mesterolone1965
norgestrel1966
quinestrol1966
pancuronium1967
pentagastrin1967
levonorgestrel1977
the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > immuno-suppressant > specific
prednisolone1955
prednisone1955
rapamycin1975
cyclosporin1976
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations allaying inflammation > [noun] > synthetic or biological
hydroxycorticosterone1943
hydrocortisone1951
cortisol1953
prednisolone1955
prednisone1955
triamcinolone1957
mefenamic acid1962
ibuprofen1967
tetracosactrin1967
1955 Jrnl. Amer. Med. Assoc. 21 May 166/1 Prednisolone (Meticortelone) and prednisone (Meticorten), two new synthetic steroids formerly known as metacortandralone and metacortandracin, have recently been recommended as effective in the treatment of rheumatoid arthritis.
1966 Lancet 24 Dec. 1382/2 He was given the usual measures for heart-failure and antibiotics, oxygen, and prednisolone 10 mg. t.d.s. to ‘buy time’.
1986 D. Potter Singing Detective i. 25 The short courses Prednisone, Prednisolone, lengthening. Then Methotrexate, after positive liver biopsies.
1998 C. Mims When we Die (1999) xii. 258 The immune system is suppressed with powerful drugs such as the steroid prednisolone, or azathioprine, or cyclosporin A.
This entry has been updated (OED Third Edition, March 2007; most recently modified version published online March 2022).
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n.1955